Searchable abstracts of presentations at key conferences in endocrinology

ea0059p038 | Adrenal and steroids | SFEBES2018

QRT-PCR analysis of the effect of in utero exposure to sewage sludge on steroidogenic gene expression in ovine foetal adrenal gland

Cooper Erin A , Reddy Sreedath , Allenson Abbie Z , Cooper Duncan P , Fowler Paul A , Rae Michael T , Morley Steven D

Endocrine disruptors are chemicals which in low concentrations can disturb gene expression in a range of endocrine glands and organs including the fetal and adult adrenal glands, potentially resulting in altered steroidogenic flux. With exposure to endocrine disruptors affecting both animals and humans, it is important to assess both the mechanisms and consequences of disruption in steroidogenic pathways, particularly as foetal development may be especially sensitive to endocr...